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“The Joys of sight restoration is incomparable with anything in the world. It is like giving life back to the living. It is for this joy that TIO (Tilganga institute of Ophthalomology) and its staff are compassionate and dedicated for... to give first class eye care.”

Lisa Ling, National geographic/MSNBC Ultimate explorer correspondent
“It was fascinating to see the (IOL manufacturing) facility. The process of making sure the IOLs are of high quality...well polished… it was amazing that
 the standards are so high. I don’t think there’s a lens factory in the world that is of a higher standard.”


Dr. Edward Wilson, Chairman, Storm Eye Institute, South Carolina, USA
 
1)   ONGOING RESEARCH PROJECTS   2)   PUBLISHED PAPERS
     
3)   INSTITUTIONAL REVIEW COMMITTEE   4)   RESEARCH COMMITTEE (RC)
     
5) MAJOR RESEARCH PROJECTS COMPLETED    
 
RESEARCH

The Research Department is the implementing body of research under the Tilganga Institute of Ophthalmology (TIO).  It conducts basic, epidemiological, survey and operational research.  The department focuses on improvement of knowledge management; patient management and helping TIO provide high quality affordable services to the underprivileged. 

The Research Committee is the governing body; they are responsible for the generation and allocation of funds for activities while also determining the research priorities.  The Institutional Review Committee is accredited by the Nepal Health Research Council and is responsible for the quality of research as well as maintaining the technical and ethical considerations in line with the Declaration of Helsinki.

From inception till 2008, the TIO Research Department has published more than thirty-five papers in national and international Medline indexed journals.  More than ten papers are currently under peer-review for publication

ONGOING RESEARCH PROJECTS

 
  • Randomized clinical trial on C-KAD Ophthalmic Solution in Patients with Loss of Visual Function due to Age-Related Nuclear Cataracts
  • Bhaktapur visual impairment and glaucoma study
  • Visual axis opacification in the children operated for the Pediatric cataract
  • Prospective study on outcome of cataract surgery in patients
  • Biometry of Pediatric Cataract at tertiary eye care centre, Nepal 
  • Effective screening program in School Children
  • Red reflex screening for Retinoblastoma early diagnosis and Treatment
  • Refractive Error (RE) Survey In central Development Region of Nepal
  • Awareness of ocular diseases in Nepalese population
  • Patient satisfaction at tertiary and community eye centre of Nepal 
  • Outcome of auto-conjunctival grafting for primary pterygia
  • Analyzing risk factors of Rhegmatogenous retinal detachment – a hospital based study
  • Predictive value of optical coherence tomography after laser photocoagulation in clinically significant macular edema in diabetic maculopathy
  • Outcome of Intravitreal  Avastin in ARMD
  • Incidence of Posterior Capsular Opacification within 1 year of SICS
  • Opportunistic screening of Glaucoma in Community Screening Camps.
  • Astigmatism changes before and after Pterygium Surgery.
  • Comparative study of endoscopic endonasal dacryocystorhinostomy and external dacryocystorhinostomy in the management of lacrimal duct obstruction
 

TIO also provides the small-scale academic research opportunities in partial fulfillment of the requirement for the Certificate in Health Science (Ophthalmology) Course. This course is run by the collaboration of Tilganga Eye Centre and Dhulikhel Medical Institute under Kathmandu University.

 MAJOR RESEARCH PROJECTS COMPLETED (Till 2008)

 
1.   The long-term results of conventional ECCE with IOL implant  
2.    Innovations in public awareness of corneal procurement
3.   The long-term results of corneal transplants in Nepal

4.   The visual results of surgery conducted in Outreach Microsurgical Eye Clinics

5.   The results of a new technique of corneal tattooing

6.   The safe use of Ketamine for anesthesia in children

7.   A prospective study of small incision, suture-less cataract surgery by Superior Section

8.   A comparison of the visual results following Temporal and Superior sections of small incision, suture-less extraction

9.   The cost recovery schemes of financial sustainability

10. Systems of effective cataract surgical delivery

11. A study of childhood cataract

12. A study of Job Satisfaction of Ophthalmologists  in Nepal

13. Socio-cultural factors influencing eye donation in Nepal

14. Health seeking bahaviour of persons having ocular trauma and its impact on complications

15. A prospective randomized clinical trial of phacoemulsification versus manual sutureless small incision extracapsular cataract surgery in Nepal

16. Prevalence of and factors associated with diabetic retinopathy among diabetes in Nepal: A Hospital based study

17. Outcome of dacryocystorhinostomy with and without silastic intubation

18. Stages of diabetic retinopathy among diabetic patient presenting for the first time at Tilganga Eye Centre

19. Outcome of dacryocystorhinostomy with and without repair of posterior flap

20. Comparison of superior and temporal approach for removal of cataract in mobile clinics of Nepal: A randomized controlled trial

21. Trachoma Rapid Assessment survey in seven districts of Nepal

22. Survey of rapid assessment of avoidable blindness in two zone (Bagmati and Janakpur)

23.  Pre operative visual acuity in subjects undergoing cataract  surgery in hospital and outreach clinics

 

PUBLISHED PAPERS (Till 2008)

 

Ocular telemedicine between Nepal and USA the Pravalance of vitreoretinal disease in rural Nepal

prevalence of vitreoretinal disease in rural Nepal. Br. J. Ophthalmol. 2009; 93; 698-699.
doi:10.1136/bjo.2008.147819
PMID: 19395632 [PubMed - indexed for MEDLINE]
 
Outcome of pneumatic retinopexy at a tertiary eye care centre in Nepal.
Thapa R, Shrestha MK, Gurung R, Ruit S, Paudyal G
Kathmandu University Medical Journal 2008; 6(24): 466-71.
 PMID:17637868 [PubMed - in Process]
Prevalence of diabetic retinopathy following a community screening for diabetes.
Paudyal G, Shrestha MK, Meyer JJ, Thapa R, Gurung R, Ruit S.
Nepal Med Coll J. 2008 Sep;10(3):160-3.
PMID: 19253859 [PubMed - indexed for MEDLINE]
 

Seasonal hyper acute pan uveitis--recent scenario in Nepal.

Manandhar A, Paudel G, Rai CK, Rai SK, Gurung R, Ruit S.
Nepal Med Coll J. 2008 Sep;10(3):196-8.
PMID: 19253866 [PubMed - indexed for MEDLINE]
 

A novel approach to glaucoma screening and education in Nepal.

Thapa SS, Kelley KH, Rens GV, Paudyal I, Chang L.
BMC Ophthalmol. 2008 Oct 26;8:21.
PMID: 18950530 [PubMed - indexed for MEDLINE]
 

Intestinal parasitosis among subjects undergoing cataract surgery at the eye camps in rural hilly areas of Nepal.

Rai SK, Gurung R, Saiju R, Bajracharya L, Rai N, Gurung K, Shakya B, Pant J, Psharma, Shrestha A, Rai CK.
Nepal Med Coll J. 2008 Jun;10(2):100-3.
PMID: 18828431 [PubMed - indexed for MEDLINE]
 

Involuntary human bite to the eyebrow.

Saiju R, Georgescu D.
Kathmandu Univ Med J (KUMJ). 2008 Apr-Jun;6(2):223-4.
PMID: 18769092 [PubMed - in process]
 

Small incision cataract surgery: tips for avoiding surgical complications.

Gurung R, Hennig A.

Community Eye Health. 2008 Mar;21(65):4-5. No abstract available.

PMID: 18504466 [PubMed - in process]

 

Prevalence of and factors associated with diabetic retinopathy among diabetics in Nepal: a hospital based study.

Shrestha MK, Paudyal G, Wagle RR, Gurung R, Ruit S, Onta SR.
Nepal Med Coll J. 2007 Dec;9(4):225-9.
PMID: 18298009 [PubMed - indexed for MEDLINE]
 

Cataract surgical outcome and gender-specific barriers to cataract services in Tilganga Eye Centre and its outreach microsurgical eye clinics in Nepal.

Gurung R.
Community Eye Health. 2007 Mar;20(61):14-5. No abstract available.
PMID: 17637868 [PubMed - in process]
 

A prospective randomized clinical trial of phacoemulsification vs manual sutureless small-incision extracapsular cataract surgery in Nepal.

Ruit S, Tabin G, Chang D, Bajracharya L, Kline DC, Richheimer W, Shrestha M, Paudyal G.
Am J Ophthalmol. 2007 Jan;143(1):32-38. Epub 2006 Sep 5.
PMID: 17188040 [PubMed - indexed for MEDLINE]
 

Viral investigation of acute hemorrhagic conjunctivitis outbreak (2003) in Nepal using molecular methods.

Kurokawa M, Rai SK, Ono K, Gurung R, Ruit S. 
Southeast Asian J Trop Med Public Health. 2006 Sep; 37(5):904-10.

PMID: 17333732 [PubMed - indexed for MEDLINE]

Patient's perception towards the eye health care system in a tertiary eye care centre in Nepal. 

 

 

 

Gurung K, Baniya B, Rai N, Pokharel NR, Shrestha MK, Poudyal G, Gurung R, Ruit S.
Nepal Med Coll J. 2006 Jun;8(2):115-7.
PMID: 17017402 [PubMed - indexed for MEDLINE]
 
  

Microbiology of dacryocystitis among adults population in southern Australia. 

 

 

 

Sainju R, Franzco AA, Shrestha MK, Ruit S.
Nepal Med Coll J. 2005 Jun;7(1):18-20.
PMID: 16295714 [PubMed - indexed for MEDLINE]
 
  

Choroidal effusion following laser peripheral iridotomy for the treatment of angle closure glaucoma in a patient with nanophthalmos. 

 

 

 

Thapa SS, Paudyal G.
Nepal Med Coll J. 2005 Jun;7(1):81-2.
PMID: 16295732 [PubMed - indexed for MEDLINE]
 
  

Treatment of vitreoretinal disorders in the developing world: indications and outcomes of vitreoretinal surgery in Nepal. 

 

 

 

Paudyal G, Doshi V, Shrestha MK, Kalayoglu MV, Tabin G, Gurung R, Shrestha B, Ruit S.
Ophthalmology. 2005 Feb;112(2):319-26.
PMID: 15691570 [PubMed - indexed for MEDLINE]
 
  

Optimal single intraocular lens power for the Nepali population. 

 

 

 

Murchison A, Richards M, Tabin G, Ruit S, Gurung R.Br J Ophthalmol. 2004 Oct;88(10):1235-6.
PMID: 15377540 [PubMed - indexed for MEDLINE]
 
  

 

 

 

Thakur J, Reddy H, Wilson ME Jr, Paudyal G, Gurung R, Thapa S, Tabin G, Ruit S.J Cataract Refract Surg. 2004 Aug;30(8):1629-35.
PMID: 15313283 [PubMed - indexed for MEDLINE]
 
 
 
Tabin GC, Gurung R, Paudyal G, Reddy HS, Hobbs CL, Wiedman MS, Ruit S.Cornea. 2004 Aug;23(6):589-96.
PMID: 15256998 [PubMed - indexed for MEDLINE]
 
 

Acute hemorrhagic conjunctivitis epidemic--2003 in Nepal.

 

 

Gurung R, Rai SK, Kurokawa M, Shrestha MK, Thakur J, Rai CK, Ruit S, Ono K.
Nepal Med Coll J. 2003 Dec;5(2):59-60.
PMID: 15024766 [PubMed - indexed for MEDLINE]

Willingness to pay for cataract surgery in Kathmandu valley. 

 

 

Shrestha MK, Thakur J, Gurung CK, Joshi AB, Pokhrel S, Ruit S.
Br J Ophthalmol. 2004 Mar;88(3):319-20.
PMID: 14977759 [PubMed - indexed for MEDLINE]

Ketamine anaesthesia for paediatric ophthalmology surgery. 

 

 

 

Pun MS, Thakur J, Poudyal G, Gurung R, Rana S, Tabin G, Good WV, Ruit S.
Br J Ophthalmol. 2003 May;87(5):535-7.
PMID: 12714385 [PubMed - indexed for MEDLINE]

Temple eye banking in Nepal. 

 

 

 

Ruit S, Tabin G, Gurung R, Shattuck T, Murchison A, Dimmig J.
Cornea. 2002 May;21(4):433-4. No abstract available.
PMID: 11973401 [PubMed - indexed for MEDLINE]

Cataract intervention in the developing world: knock-on development through mentoring hospitals. 

 

 

Ruit S, Brian G, Moran D, Tabin G.
Clin Experiment Ophthalmol. 2000 Feb;28(1):71-2. No abstract available.
PMID: 11345354 [PubMed - indexed for MEDLINE]

 A innovation in developing world cataract surgery: sutureless extracapsular cataract extraction with intraocular lens implantation.  

  

 

Ruit S, Paudyal G, Gurung R, Tabin G, Moran D, Brian G.
Clin Experiment Ophthalmol. 2000 Aug;28(4):274-9.
PMID: 11021556 [PubMed - indexed for MEDLINE]

 Author's reply 

  

 

Tabin G, Ruit S.
Ophthalmology. 2000 Oct;107(10):1797. No abstract available.
PMID: 11013159 [PubMed - as supplied by publisher]
 

Low-cost high-volume extracapsular cataract extraction with posterior chamber intraocular lens implantation in Nepal. 

 

 

 

Ruit S, Tabin GC, Nissman SA, Paudyal G, Gurung R.
Ophthalmology. 1999 Oct;106(10):1887-92.
PMID: 10519581 [PubMed - indexed for MEDLINE]
 

 

 

 

Gillies M, Brian G, La Nauze J, Le Mesurier R, Moran D, Taylor H, Ruit S.
Arch Ophthalmol. 1998 Jan;116(1):90-2. Review.
PMID: 9445213 [PubMed - indexed for MEDLINE]

 Extracapsular cataract extraction in Nepal. 2-year outcome. 

 

 

 

Ruit S, Robin AL, Pokhrel RP, Sharma A, DeFaller J.
Arch Ophthalmol. 1991 Dec;109(12):1761-3.
PMID: 1841591 [PubMed - indexed for MEDLINE]

Long-term results of extracapsular cataract extraction and posterior chamber intraocular lens insertion in Nepal.

 

 

 

Ruit S, Robin AL, Pokhrel RP, Sharma A, DeFaller J, Maguire PT. 
Trans Am Ophthalmol Soc. 1991;89:59-72; discussion 72-6.
PMID: 1808818 [PubMed - indexed for MEDLINE]

On the practicalities of eye camp cataract extraction and intraocular lens implantation in Nepal. 

 

 

Ruit S, Brian G, Hollows F.
Ophthalmic Surg. 1990 Dec;21(12):862-5.
PMID: 2096350 [PubMed - indexed for MEDLINE]

 

 

 

Saiju R, Morse L J, Weinberg D, Shrestha M K and Ruit S. 
 Br. J. Ophthalmol. Published online 9 Jun 2009;
doi:10.1136/bjo.2008.147819
 
 
Limbu B, Saiju R, Ruit S.
(2009), Vol. 7, No. 2, Issue 26, 115-119
 
Ulrich J N, Poudyal G, Marks S J, Vrabec T R, Marks B, Thapa A B S, Shrestha M K, Ruit S, Federman J L
. Br. J. Ophthalmol. 2009; 93; 698-699.
 
 
Bajracharya L, Shah DN, Raut KB and Koirala S.
(Nepal Med Coll J 2008; 10(4): 209-214
 

INSTITUTIONAL REVIEW COMMITTEE (IRC)

Keeping in view of significance of research in the quality service and other academic activities, TIO has constituted a IRC.

The IRC is formulated by five members. It is chaired by deputy medical director of Tilganga eye centre. One member is invited from outside of this centre. This IRC has accredited by NHRC. It follows the all rules and regulations of NHRC in conducting each and every research activities.
The Committee members of IRC are as follows:

Chairperson- Dr. Reeta Gurung

Member- Dr. Govinda Paudyal

Member- Dr. Suman Sumser Thapa

Member- Dr. Shiba Kumar Rai

Member Secretary- Mr. Mohan Krishna Shrestha

 

TIO- IRC looks after the all activities at TIO. IRC also organized three days research methodology and writing scientific paper training for faculty of MD residency and other managerial staffs of Tilganga institute of Ophthalomolog.

In house research competition is going to start from this year through the Tilganga eye centre basket fund created by own budget.

 

RESEARCH COMMITTEE (RC)

Tilganga institute of Ophthalomolog has formulated the research committee under the chair of Medical Director of centre with six members. It will help to manage the all research activities under the Tilganga institute of Ophthalomolog.

The Committee members of RC are as follows:

Chairperson- Prof. Sanduk Ruit

Member- Dr. Reeta Gurung

Member- Dr. Govinda Paudyal

Member- Dr. Suman Sumser Thapa

Member- Mr. Nabin Kumar Rai

Member- Finance Manager, TIO

Member Secretary- Mr. Mohan Krishna Shrestha

 

 

For further information please mail to research @tilganga.com.np.
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